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Lengthy COVID, open-access boundaries and tobacco cash

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A medical worker prepares a dose of Pfizer-BioNTech COVID-19 vaccine during a vaccination campaign in Slovenia.

A medical employee prepares a dose of the Pfizer–BioNTech COVID-19 vaccine, which has been broadly administered in Israel.Credit score: Luka Dakskobler/SOPA Pictures/LightRocket/Getty

Lengthy-COVID signs much less doubtless in vaccinated individuals, Israeli knowledge say

Knowledge from individuals contaminated with SARS-CoV-2 early within the pandemic add to rising proof suggesting that vaccination may also help to cut back the danger of lengthy COVID (P. Kuodi et al. Preprint at medRxiv https://doi.org/hd29; 2022).

Scientists in Israel report that individuals who have each been contaminated with SARS-CoV-2 and obtained doses of the Pfizer–BioNTech vaccine are a lot much less prone to report any of a spread of widespread long-COVID signs than are individuals who had been unvaccinated when contaminated. In actual fact, vaccinated individuals are no extra prone to report signs than individuals who have by no means caught SARS-CoV-2. The examine has not but been peer reviewed.

“Right here is one more reason to get vaccinated, when you wanted one,” says co-author Michael Edelstein, an epidemiologist at Bar-Ilan College in Safed, Israel.

Folks with lengthy COVID have signs, akin to fatigue, lengthy after SARS-CoV-2 an infection.

In idea, vaccination might defend towards the situation by shortening the virus’s free rein within the physique throughout breakthrough infections. However the few research analyzing whether or not vaccines defend towards lengthy COVID have had blended outcomes, says Akiko Iwasaki, a viral immunologist on the Yale Faculty of Drugs in New Haven, Connecticut.

To be taught extra, between July and November 2021, Edelstein and his co-authors requested some 3,000 individuals whether or not they had been experiencing the commonest lengthy COVID signs. All had been examined for SARS-CoV-2 between March 2020 and the examine interval.

The researchers in contrast the prevalence of every symptom with self-reported vaccination standing and located that totally vaccinated contributors who had additionally had COVID-19 had been 54% much less prone to report complications, 64% much less prone to report fatigue and 68% much less prone to report muscle ache than had been their unvaccinated counterparts. Edelstein says his group’s outcomes echo these of different analysis, together with a UK-based examine (M. Antonelli et al. Lancet Infect. Dis. 22, 43–55; 2022) from final September that discovered that vaccination halved the danger of lengthy COVID.

Claire Steves, a geriatrician at King’s School London who led the UK examine, agrees that the Israeli knowledge assist earlier findings. “It’s actually good to see completely different examine designs correlating, with the identical outcomes,” she says.

Excessive prices of open-access publishing deter authors

The charges that journals cost to publish researchers’ work open entry are a barrier for authors in low- and middle-income nations, an evaluation finds.

Extra tutorial journals have been making their articles free to learn, pushed partially by open-access necessities from analysis funders. Though this has made extra of the scholarly literature accessible, many scientists have famous the excessive article-processing fees (APCs) required to publish open-access papers in some titles.

Researchers examined greater than 37,000 articles revealed by Elsevier in 38 ‘hybrid’ journals, which comprise each paywalled and freely accessible articles, and their ‘mirror’ titles — totally open-access variations of these journals (A. C. Smith et al. Quant. Sci. Stud. https://doi.org/gn38g5; 2021). The APCs for the mirror journals value a median of US$2,600. Round 80% of articles in mirror journals had lead authors from high-income nations, and none had authors from low-income nations.

“After we see outcomes like this, it simply makes it crystal clear that there’s a very robust monetary barrier for publishing when journals cost APCs,” says Rafael Zenni, an ecologist on the Federal College of Lavras in Brazil.

A pack of Philip Morris Marlboro brand cigarettes.

Philip Morris Worldwide owns numerous cigarette manufacturers, together with Marlboro.Credit score: Daniel Acker/Bloomberg through Getty

Publishing ban for tobacco-funded researchers

A gaggle of worldwide respiratory societies has banned researchers related to tobacco corporations from publishing papers of their journals, after the controversial acquisition by a tobacco big of a health-care agency that makes inhalers.

Final 12 months, the Swiss-American tobacco firm Philip Morris Worldwide, which owns a number of the world’s standard cigarette manufacturers, took over UK-based pharmaceutical agency Vectura. In response, six well being our bodies, together with the American Thoracic Society, the European Respiratory Society and the Worldwide Union In opposition to Tuberculosis and Lung Ailments, have issued a joint assertion describing the transfer as “extremely unethical and inappropriate”.

Respiratory societies have banned researchers instantly funded by tobacco corporations for greater than a decade. Now, the organizations have prolonged that ban to researchers working for companies acquired by tobacco corporations.

The assertion says that workers of such corporations won’t be allowed to publish within the societies’ journals or current at conferences, and recommends that individuals don’t use medical merchandise newly developed by tobacco-owned companies.

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